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Generation and characterization of Kctd15 mutations in zebrafish.

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Potassium channel tetramerization domain containing 15 (Kctd15) was previously found to have a role in early neural crest (NC) patterning. specifically delimiting the region where NC markers are expressed via repression of transcription factor AP-2a and inhibition of Wnt signaling. We used transcription activator-like effector nucleases (TALENs) to generate null mutations in zebrafish... https://www.roneverhart.com/SWW-x-SXSW-Cake-Something-Was-Wrong-2-8x3/
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